Description

2-(4-Biphenylyl)-2,2-Difluoroacetic Acid is a specialized fluorinated organic acid building block with a biphenyl core structure. This compound is valued for its unique molecular architecture, which combines aromaticity with a reactive difluoroacetic acid moiety, making it a versatile intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating fluorinated aromatic compounds used in electronic display technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to impart specific thermal and chemical resistance properties to high-performance polymers.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a fluorinated analog in structure-activity relationship (SAR) studies.
• Material Science Research: Investigated for use in the development of metal-organic frameworks (MOFs) and other functional materials.

Basic Information

Product Name	2-(4-Biphenylyl)-2,2-Difluoroacetic Acid
CAS No.	73790-13-3
Molecular Formula	C₁₄H₁₀F₂O₂
Molecular Weight	248.22 g/mol
Synonyms	2,2-Difluoro-2-(4-phenylphenyl)acetic Acid; [1,1'-Biphenyl]-4-acetic Acid, 2,2-Difluoro-; 4-Biphenylyldifluoroacetic Acid; α,α-Difluoro-4-phenylbenzeneacetic Acid; 2-(4-Phenylphenyl)-2,2-difluoroacetic Acid; Difluoro(biphenyl-4-yl)acetic Acid; (4-Biphenylyl)difluoroacetic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Biphenylyl)-2,2-Difluoroacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.