Description

Ethyl 2,2-Difluoro-2-(1-Naphthyl)Acetate is a high-purity fluorinated organic building block characterized by its naphthyl and difluoroacetate ester functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research institutions and industrial manufacturers engaged in developing active ingredients, advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoroacetate group can impart specific biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex molecular architectures, including in cross-coupling reactions and as a substrate for catalyst development.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on chemical reactivity and physical properties in organic molecules.

Basic Information

Item	Detail
Product Name	Ethyl 2,2-Difluoro-2-(1-Naphthyl)Acetate
CAS No.	73790-00-8
Molecular Formula	C₁₄H₁₂F₂O₂
Molecular Weight	250.24 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(naphthalen-1-yl)acetate; 1-Naphthaleneacetic acid, 2,2-difluoro-, ethyl ester; 2,2-Difluoro-2-(1-naphthyl)acetic acid ethyl ester; Ethyl α,α-difluoro-1-naphthaleneacetate; Ethyl 1-naphthyl(difluoro)acetate; 73790-00-8; Ethyl (difluoro)(1-naphthyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-2-(1-Naphthyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.