Description

Ethyl 2-(4-Biphenylyl)-2,2-Difluoroacetate is a specialized fluorinated organic ester, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its unique structure, featuring a biphenyl core and a difluoroacetate moiety, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where precise fluorination is required to modulate bioactivity, metabolic stability, and physical characteristics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to enhance potency and pharmacokinetics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the difluoroacetate group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Advanced Polymer Chemistry: Monomer or modifier for creating specialty polymers with enhanced thermal stability, chemical resistance, or specific optical properties.
• Organic Synthesis & Catalysis Research: Valuable reagent in academic and industrial R&D for studying fluorination reactions and developing new catalytic methodologies.
• Fluorinated Fine Chemicals: Intermediate for producing other high-value fluorinated fine chemicals and dyes.

Basic Information

Item	Details
Product Name	Ethyl 2-(4-Biphenylyl)-2,2-Difluoroacetate
CAS No.	73789-98-7
Molecular Formula	C16H14F2O2
Molecular Weight	276.28 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(4-phenylphenyl)acetate; 2-(4-Biphenylyl)-2,2-difluoroacetic Acid Ethyl Ester; Ethyl [1,1'-Biphenyl]-4-yl(difluoro)acetate; Difluoro(4-phenylphenyl)acetic Acid Ethyl Ester; 73789-98-7; Ethyl 4-Biphenylyldifluoroacetate; Ethyl α,α-Difluoro-4-phenylbenzeneacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Biphenylyl)-2,2-Difluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.