Description

All-trans-2-Retinylidene-5-p-Methoxyphenyl-1,3-Cyclohexanedione is a specialized retinoid-derived compound, a key intermediate in the synthesis of advanced pharmaceutical and cosmetic actives. This molecule matters for its role in developing novel therapeutic agents and high-performance skincare formulations targeting cellular differentiation and photo-protection. It is primarily needed by research institutions, pharmaceutical R&D departments, and manufacturers of premium cosmetic ingredients focused on anti-aging and dermatological applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel retinoid-based drugs for dermatology and oncology.
• Cosmetic Active Ingredient R&D: Used in the development of next-generation anti-aging, skin-renewal, and photoprotective formulations.
• Biochemical Research: Serves as a reference standard and probe in studies of retinoid receptor pathways and cellular signaling.
• Organic Synthesis: A versatile synthon for constructing complex polycyclic structures in medicinal chemistry.
• Nutraceutical Development: Investigated for potential applications in advanced dietary supplements targeting skin health.

Basic Information

Product Name	All-trans-2-Retinylidene-5-p-Methoxyphenyl-1,3-Cyclohexanedione
CAS No.	73685-21-9
Molecular Formula	C29H30O3
Molecular Weight	426.55 g/mol
Synonyms	2-[(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ylidene]-5-(4-methoxyphenyl)cyclohexane-1,3-dione; Retinylidene Methoxyphenyl Cyclohexanedione; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ylidene-5-(p-methoxyphenyl)-1,3-cyclohexanedione; All-trans-Retinylidene-p-Methoxyphenyl Cyclohexanedione; 73685-21-9
EINECS	Contact for details

Quality Control

Our All-trans-2-Retinylidene-5-p-Methoxyphenyl-1,3-Cyclohexanedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets precise customer specifications for research and development purposes. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
All-trans Isomer Content	≥ 90.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.