Description

n-(Sodiooxy)-4-(Trifluoromethyl)Benzenemethanimine is a specialized organofluorine building block and a key intermediate in advanced organic synthesis. Its value lies in its unique structure, which incorporates both a reactive imine and a trifluoromethyl group, enabling the efficient introduction of fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and bioavailability. The CAS number for this product is 73664-63-8.

Application

This versatile intermediate is primarily used in the synthesis of complex, high-value fluorinated compounds. Its applications include:

• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) with trifluoromethyl groups for improved drug potency and pharmacokinetics.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where fluorine substitution enhances biological activity and environmental persistence.
• Material Science Research: Precursor for fluorinated polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: Serving as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex aryl-fluorinated architectures.
• Fine Chemical Production: Intermediate in the custom synthesis of specialty fluorinated fine chemicals and dyes.

Basic Information

Product Name	n-(Sodiooxy)-4-(Trifluoromethyl)Benzenemethanimine
CAS No.	73664-63-8
Molecular Formula	C8H5F3NNaO
Molecular Weight	219.12 g/mol
Synonyms	4-(Trifluoromethyl)benzaldehyde oxime sodium salt; Sodium (Z)-N-hydroxy-4-(trifluoromethyl)benzenecarboximidate; Benzenemethanimine, N-(sodiooxy)-4-(trifluoromethyl)-; (Z)-4-(Trifluoromethyl)benzaldehyde oxime sodium salt; Sodium (E)-N-hydroxy-4-(trifluoromethyl)benzenecarboximidate; p-(Trifluoromethyl)benzaldoxime sodium salt; α-(Sodiooxyimino)-4-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our production of n-(Sodiooxy)-4-(Trifluoromethyl)Benzenemethanimine adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC/NMR), impurity profile, and moisture content. Our quality system is designed to support cGMP compliance for pharmaceutical applications and meets the exacting standards required for research and commercial scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.