Description

2-(2-Chloro-1,1,2,2-Tetrafluoroethoxy)-1,1,2,2-Tetrafluoro-Ethanesulfonyl Fluoride is a high-value, specialty fluorinated building block critical for advanced synthesis. Its unique structure, featuring both a sulfonyl fluoride and a polyfluoroether moiety, makes it an indispensable reagent for introducing functional, fluorinated segments into target molecules. This compound is primarily sought by R&D and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves metabolic stability and bioactivity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance fluoropolymers with exceptional chemical resistance, thermal stability, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystals and dielectric fluids for electronics applications.
• Sulfonyl Fluoride "Click Chemistry": The sulfonyl fluoride group enables its use in SuFEx (Sulfur Fluoride Exchange) click chemistry, a powerful tool for bioconjugation and polymer ligation.
• Organic Synthesis Reagent: Acts as a versatile electrophile for introducing the -SO2F group and complex fluorinated ether chains into organic frameworks under controlled conditions.

Basic Information

Item	Details
Product Name	2-(2-Chloro-1,1,2,2-Tetrafluoroethoxy)-1,1,2,2-Tetrafluoro-Ethanesulfonyl Fluoride
CAS No.	73605-98-8
Molecular Formula	C4ClF9O3S
Molecular Weight	328.54 g/mol
Synonyms	1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoro-2-chloroethoxy)ethanesulfonyl fluoride; Tetrafluoro(2-chlorotetrafluoroethoxy)ethanesulfonyl fluoride; Perfluoro(2-chloroethoxyethyl) sulfonyl fluoride; FESF derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Chloro-1,1,2,2-Tetrafluoroethoxy)-1,1,2,2-Tetrafluoro-Ethanesulfonyl Fluoride is manufactured and analyzed under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and FTIR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.