Description

1,2-Dilauroyl-Sn-Glycero-3-Phosphorylglycerol CAS NO 73548-69-3 is a synthetic, anionic phospholipid derivative, specifically a phosphatidylglycerol (PG) with two lauric acid (C12:0) chains. This compound is valued for its role as a critical functional excipient and membrane component in advanced pharmaceutical and biotechnological formulations. It is primarily required by manufacturers in the liposome and lipid nanoparticle (LNP) drug delivery sector, as well as in research for modeling biological membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key anionic lipid component used to create stable, targeted drug delivery systems for mRNA vaccines, cancer therapeutics, and other encapsulated actives.
• Biomimetic Membrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study lipid-protein interactions, membrane fusion, and permeability.
• Pharmaceutical Excipient: Functions as a stabilizer and emulsifying agent in complex injectable and topical formulations to enhance bioavailability.
• Diagnostic Reagent Preparation: Employed in the development of diagnostic assays and kits that require specific membrane environments or liposomal carriers.
• Cosmetic & Dermal Delivery Systems: Incorporated into advanced cosmetic products for its emulsifying properties and ability to facilitate the skin delivery of active ingredients.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies involving phospholipases or lipid metabolism pathways.

Basic Information

Product Name	1,2-Dilauroyl-Sn-Glycero-3-Phosphorylglycerol
CAS No.	73548-69-3
Molecular Formula	C30H57O10P
Molecular Weight	608.74 g/mol
Synonyms	1,2-Dilauroyl-sn-glycero-3-phospho-(1'-rac-glycerol); DLPG; PG(12:0/12:0); 1,2-Didodecanoyl-sn-glycero-3-phosphoglycerol; Phosphatidylglycerol (12:0/12:0); 1,2-Dilauroylphosphatidylglycerol; 3-sn-Phosphatidyl-1'-sn-glycerol (dilauroyl); L-α-Phosphatidylglycerol (dilauroyl)
EINECS	Contact for details

Quality Control

Our 1,2-Dilauroyl-Sn-Glycero-3-Phosphorylglycerol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in water
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.