Description

(4R)-10-Hydroxy-9α-Methyl-20-Norkaur-16-En-18-Oic Acid 18,10-Lactone is a high-purity, structurally defined diterpenoid lactone compound. This compound serves as a critical intermediate and reference standard in advanced organic synthesis and pharmaceutical research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for the development of novel therapeutic agents and complex natural product syntheses.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex diterpenoid-based drug candidates.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Organic Synthesis: Versatile starting material or intermediate for constructing complex natural product analogs and novel chemical entities.
• Biochemical Research: Tool compound for studying biological pathways and enzyme interactions related to diterpenoid metabolism.
• Process Chemistry: Used in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	(4R)-10-Hydroxy-9α-Methyl-20-Norkaur-16-En-18-Oic Acid 18,10-Lactone
CAS No.	73483-88-2
Molecular Formula	C₂₀H₂₈O₃
Molecular Weight	316.44 g/mol
Synonyms	10-Hydroxy-9α-methyl-20-norkaur-16-en-18-oic acid 18,10-lactone; (4R)-Kaur-16-en-18-oic acid, 10-hydroxy-9α-methyl-, 18,10-lactone; 9α-Methyl-10-hydroxy-20-norkaur-16-en-18-oic acid γ-lactone; 18,10-Lactone of 10-hydroxy-9α-methyl-20-norkaur-16-en-18-oic acid; Diterpenoid Lactone 73483-88-2; Kaurane diterpene lactone derivative; (4R)-enantiomer of the specified lactone.
EINECS	Contact for details

Quality Control

Our (4R)-10-Hydroxy-9α-Methyl-20-Norkaur-16-En-18-Oic Acid 18,10-Lactone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (4R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.