Description

(2S)-2-[(3S,6S)-6-[2-[(1S,2R,4Aα,8Aβ)-Decahydro-1,2α,4A-Trimethyl-5-Methylenenaphthalen-1β-Yl]Ethyl]-6-Methyl-1,2-Dioxan-3-Yl]Propanoic Acid is a high-purity, stereochemically defined diterpenoid derivative with a complex polycyclic structure. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, particularly for the development of bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical sectors for constructing complex natural product analogs and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex diterpenoids and other natural products for structure-activity relationship (SAR) studies.
• Chemical Biology Probe Development: Serves as a precursor for labeled compounds or molecular probes to study biological pathways and target engagement.
• Advanced Material Research: Potential use in the development of chiral catalysts or ligands for asymmetric synthesis applications.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S)-2-[(3S,6S)-6-[2-[(1S,2R,4Aα,8Aβ)-Decahydro-1,2α,4A-Trimethyl-5-Methylenenaphthalen-1β-Yl]Ethyl]-6-Methyl-1,2-Dioxan-3-Yl]Propanoic Acid
CAS No.	73436-44-9
Molecular Formula	C24H38O4
Molecular Weight	390.56 g/mol
Synonyms	Abietic Acid Derivative; Diterpenoid Propanoic Acid; (2S,3S,6S,1'S,2'R)-Isomer; 13-Abieten-18-oic acid, 8,11,13-abietatrien-18-oic acid derivative; Labdane diterpene derivative; 5-Methylenenaphthalen-1β-yl propanoic acid isomer; CAS 73436-44-9
EINECS	Contact for details

Quality Control

Our (2S)-2-[(3S,6S)-6-[2-[(1S,2R,4Aα,8Aβ)-Decahydro-1,2α,4A-Trimethyl-5-Methylenenaphthalen-1β-Yl]Ethyl]-6-Methyl-1,2-Dioxan-3-Yl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.