Description

2-Bromo-1-(2,3-Dihydro-1H-Indol-1-Yl)-1-Ethanone is a versatile and high-purity brominated ketone building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scale-up activities. Our supply is characterized by stringent quality control and reliable batch-to-batch consistency to support your most demanding R&D and production needs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating novel heterocyclic molecules for crop protection agents and pesticide development.
• Organic Synthesis Reagent: Serves as an electrophilic alkylating agent for introducing the 2-bromoacetyl moiety into nitrogen-containing heterocycles under mild conditions.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers and advanced organic materials with unique electronic properties.

Basic Information

Product Name	2-Bromo-1-(2,3-Dihydro-1H-Indol-1-Yl)-1-Ethanone
CAS No.	73392-01-5
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	1-(2-Bromoacetyl)indoline; 2-Bromo-1-indolin-1-ylethanone; N-(2-Bromoacetyl)indoline; 2-Bromo-1-(2,3-dihydroindol-1-yl)ethanone; Indoline, 1-(2-bromoacetyl)-; Ethanone, 2-bromo-1-(2,3-dihydro-1H-indol-1-yl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(2,3-Dihydro-1H-Indol-1-Yl)-1-Ethanone is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and identity. Our quality protocols are designed to support cGMP-compliant applications where required. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles is provided with each shipment to guarantee full traceability and batch consistency for your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.