Description

4-Chloromethylbenzaldehyde; >95% is a versatile aromatic aldehyde building block, characterized by its reactive chloromethyl and formyl functional groups. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where it serves as a key precursor for active ingredients and fine chemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing benzyl-protected intermediates and other advanced structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with benzyl-protected amine or alcohol functionalities.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its reactive sites for constructing complex heterocyclic systems.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the production of specialty polymers and resins, where it can be incorporated to modify thermal or mechanical properties.
• Fine Chemical and Dye Intermediate: Utilized in the multi-step synthesis of complex dyes, pigments, and other high-value fine chemicals.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, for carbon-carbon bond formation.

Basic Information

Product Name	4-Chloromethylbenzaldehyde; >95%
CAS No.	73291-09-5
Molecular Formula	C8H7ClO
Molecular Weight	154.59 g/mol
Synonyms	4-(Chloromethyl)benzaldehyde; p-(Chloromethyl)benzaldehyde; α-Chloro-p-tolualdehyde; 4-Formylbenzyl chloride; Benzaldehyde, 4-(chloromethyl)-; Terephthalaldehyde monochloride; p-Chloromethylbenzaldehyde; 1-Chloromethyl-4-formylbenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Chloromethylbenzaldehyde; >95% undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/GC), identity confirmation (by IR/NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	> 95.0%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.