Description

2-Hydroxy-6-Methyl-Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a nitrile group, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or benzoxazole scaffolds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in coordination chemistry to create chelating ligands for metal catalysts.
• Polymer Chemistry: Monomer or modifier for producing high-performance engineering plastics and resins.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized colorants and optical brighteners.
• Organic Synthesis Research: Versatile starting material for academic and industrial R&D exploring new heterocyclic compounds.

Basic Information

Product Name	2-Hydroxy-6-Methyl-Benzonitrile
CAS No.	73289-66-4
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	6-Methyl-2-hydroxybenzonitrile; 2-Cyano-3-methylphenol; 2-Hydroxy-6-methylbenzonitrile; 3-Methyl-2-hydroxybenzonitrile; 6-Methylsalicylonitrile; o-Hydroxy-m-tolunitrile; 2-Methyl-6-cyanophenol; 6-Methyl-2-cyanophenol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methyl-Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.