Description

Cyclopropanecarboxylic Acid, 2-Cyano-2-Methyl-, Ethyl Ester, cis- (9Ci) is a specialized cis-configured cyclopropane derivative, valued as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique sterically constrained three-membered ring and functional groups make it essential for constructing complex molecular architectures with high stereochemical fidelity. This high-purity intermediate is primarily demanded by the pharmaceutical, agrochemical, and advanced materials research sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane ring contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic complexes.
• Advanced Materials Research: Acts as a monomer or functional modifier in the development of polymers with specific optical or mechanical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its rigid structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Cyano-2-Methyl-, Ethyl Ester, cis- (9Ci)
CAS No.	73178-42-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	cis-2-Cyano-2-methylcyclopropanecarboxylic acid ethyl ester; Ethyl cis-2-cyano-2-methylcyclopropanecarboxylate; cis-Ethyl 2-cyano-2-methylcyclopropanecarboxylate; 2-Cyano-2-methylcyclopropanecarboxylic acid ethyl ester, cis-; (1R,2S)-rel-2-Cyano-2-methylcyclopropanecarboxylic Acid Ethyl Ester; (1S,2R)-rel-2-Cyano-2-methylcyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 2-cyano-2-methyl-, ethyl ester, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Cyano-2-Methyl-, Ethyl Ester, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, precise stereochemical integrity (cis-isomer content), and consistent performance as a synthetic intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
cis-Isomer Content (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.