Description

1-(2-Chloro-5-Methyl-Phenyl)-Ethanone is a specialized aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with both a reactive carbonyl group and a halogen substituent, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers.
• Fine Chemical Production: Acts as a versatile intermediate for manufacturing dyes, pigments, and other performance chemicals.

Basic Information

Product Name	1-(2-Chloro-5-Methyl-Phenyl)-Ethanone
CAS No.	73129-52-9
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	2'-Chloro-5'-Methylacetophenone; 1-Acetyl-2-chloro-5-methylbenzene; 2-Chloro-5-methylacetophenone; 2-Chloro-5-methylphenyl methyl ketone; (2-Chloro-5-methylphenyl)ethanone; o-Chloro-p-methylacetophenone; CAS 73129-52-9
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-5-Methyl-Phenyl)-Ethanone adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for use as a pharmaceutical intermediate, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.