Description

Sulfadimethoxine-D6 is a deuterium-labeled internal standard of the sulfonamide antibiotic sulfadimethoxine, specifically designed for analytical applications. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily used by research scientists and quality control laboratories in the pharmaceutical, veterinary medicine, and food safety sectors for precise method development and validation.

Application

• Quantitative Mass Spectrometry: Serves as a critical internal standard for the accurate quantification of sulfadimethoxine in complex biological matrices using LC-MS/MS and GC-MS.
• Pharmaceutical Research: Used in pharmacokinetic and metabolism studies to track the absorption, distribution, and excretion of sulfadimethoxine.
• Veterinary Drug Residue Analysis: Enables precise monitoring of sulfadimethoxine residues in animal-derived food products (meat, milk, eggs) to ensure compliance with maximum residue limits (MRLs).
• Method Development & Validation: Provides a stable isotopic reference for developing and validating robust analytical methods in compliance with guidelines like FDA 21 CFR and EU regulations.
• Clinical Diagnostics: Supports research into therapeutic drug monitoring and diagnostic assay development.
• Environmental Testing: Facilitates the trace analysis of veterinary antibiotic pollutants in water and soil samples.

Basic Information

Product Name	Sulfadimethoxine-D6
CAS No.	73068-02-7
Molecular Formula	C12H8D6N4O4S
Molecular Weight	314.36 g/mol
Synonyms	4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide-d6; Sulfadimethoxine (hexadeuterated); Sulfadimethoxine-d6; [2H6]-Sulfadimethoxine; Sulfadimethoxine Internal Standard; Deuterated Sulfadimethoxine; SDM-d6
EINECS	Contact for details

Quality Control

Every batch of Sulfadimethoxine-D6 is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment to meet the exacting demands of analytical reference standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for isotopic purity, chemical purity (by HPLC), and identity confirmation (by NMR and MS).

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.