Description

5-Chloro-2,2-Difluoro-1,3-Benzodioxole is a high-value, multi-functional halogenated benzodioxole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those requiring the difluoromethylene-dioxole moiety.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity.
• Material Science Precursor: Acts as a monomer or modifier in the development of specialty polymers and high-performance materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocyclic compounds in research laboratories.
• Ligand and Catalyst Development: Useful for creating novel ligands in catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Chloro-2,2-Difluoro-1,3-Benzodioxole
CAS No.	72769-08-5
Molecular Formula	C7H3ClF2O2
Molecular Weight	192.55 g/mol
Synonyms	5-Chloro-2,2-difluoro-1,3-benzodioxole; 1,3-Benzodioxole, 5-chloro-2,2-difluoro-; 2,2-Difluoro-5-chloro-1,3-benzodioxole; 5-Chloro-2,2-difluorobenzo[d][1,3]dioxole; 72769-08-5; 5-Chloro-2,2-difluoro-benzo[1,3]dioxole
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,2-Difluoro-1,3-Benzodioxole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.