Description

Ethyl 3-[(Phenylsulfonyl)Methyl]-1,2,4-Oxadiazole-5-Carboxylate is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific enzyme pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those containing the 1,2,4-oxadiazole pharmacophore known for its diverse biological activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique sulfonyl and oxadiazole functionalities.
• Chemical Biology Probe Synthesis: Employed in creating specialized molecules for studying biological processes and identifying new therapeutic targets.
• Material Science Research: Acts as a building block for novel polymers or organic electronic materials due to its conjugated system and functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Ethyl 3-[(Phenylsulfonyl)Methyl]-1,2,4-Oxadiazole-5-Carboxylate
CAS No.	72660-82-3
Molecular Formula	C12H12N2O5S
Molecular Weight	296.30 g/mol
Synonyms	Ethyl 3-(Phenylsulfonylmethyl)-1,2,4-oxadiazole-5-carboxylate; 5-(Ethoxycarbonyl)-3-[(phenylsulfonyl)methyl]-1,2,4-oxadiazole; 1,2,4-Oxadiazole-5-carboxylic acid, 3-[(phenylsulfonyl)methyl]-, ethyl ester; Ethyl 3-(benzenesulfonylmethyl)-1,2,4-oxadiazole-5-carboxylate; 72660-82-3; Ethyl 3-(Phenylsulfonylmethyl)-1,2,4-oxadiazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-[(Phenylsulfonyl)Methyl]-1,2,4-Oxadiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.