Description

(7Z,18R)-14,18-Epoxy-3,25-Dihydroxyophiobol-7(25)-En-5-One is a highly functionalized ophiobolin derivative, a class of sesterterpenoids known for their complex biological activities. This compound is of significant interest for its role as a key intermediate and reference standard in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D scientists and process chemists in the life sciences sector for the development of novel bioactive molecules. The compound's unique epoxy and dihydroxy functional groups make it a valuable scaffold for chemical synthesis and biological evaluation.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis of novel drug candidates, particularly in oncology and antimicrobial therapy research.
• Agrochemical Discovery: Used as a lead compound or synthetic precursor in the development of new fungicides and plant growth regulators, leveraging the bioactivity of ophiobolin analogs.
• Biochemical Studies: Employed as a tool compound to investigate specific biological pathways and enzyme interactions due to its defined stereochemistry and functional groups.
• Academic Research: Utilized in university and institutional laboratories for synthetic organic chemistry projects and the study of sesterterpenoid biosynthesis.
• High-Purity Reference Material: Supplied as an analytical standard for quality control and method development in laboratories requiring precise quantification of ophiobolin derivatives.

Basic Information

Product Name	(7Z,18R)-14,18-Epoxy-3,25-Dihydroxyophiobol-7(25)-En-5-One
CAS No.	72657-12-6
Molecular Formula	C25H38O5
Molecular Weight	418.57 g/mol
Synonyms	14,18-Epoxy-3,25-dihydroxyophiobol-7(25)-en-5-one; Ophiobolin I; 6-epi-Ophiobolin I; (7Z,18R)-14,18-Epoxy-3,25-dihydroxyophiobola-7,25-dien-5-one; (3β,5β,18R)-14,18-Epoxy-3,25-dihydroxyophiobol-7(25)-en-5-one; 72657-12-6; Ophiobolin derivative
EINECS	Contact for details

Quality Control

Our (7Z,18R)-14,18-Epoxy-3,25-Dihydroxyophiobol-7(25)-En-5-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Allow the container to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.