Description

3,4,6-Tri-o-Benzyl-2-Deoxy-D-Glucono-1,5-Lactone is a key protected carbohydrate intermediate, specifically a benzylated deoxy sugar lactone. This compound is valued for its role as a versatile chiral building block in complex organic synthesis, enabling the stereoselective construction of biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified nucleosides and carbohydrate-based therapeutics.
• Antiviral Drug Research: Used in the development of novel antiviral compounds, including potential treatments for HIV and hepatitis.
• Glycochemistry: Serves as a protected glycosyl donor or acceptor for constructing complex oligosaccharides and glycoconjugates.
• Chiral Pool Synthesis: Provides a source of chirality for the asymmetric synthesis of natural products and other high-value targets.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug candidates.
• Process Chemistry: Used in scale-up and route development for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3,4,6-Tri-o-Benzyl-2-Deoxy-D-Glucono-1,5-Lactone
CAS No.	72605-77-7
Molecular Formula	C27H28O5
Molecular Weight	432.51 g/mol
Synonyms	2-Deoxy-3,4,6-tri-O-benzyl-D-glucono-1,5-lactone; 3,4,6-Tri-O-benzyl-2-deoxy-D-glucono-1,5-lactone; 2-Deoxy-3,4,6-tri-O-benzyl-D-glucose 1,5-lactone; Tri-O-benzyl-2-deoxygluconolactone; 2-Deoxy-D-glucono-1,5-lactone 3,4,6-tribenzyl ether; D-Glucono-1,5-lactone, 2-deoxy-3,4,6-tris-O-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our 3,4,6-Tri-o-Benzyl-2-Deoxy-D-Glucono-1,5-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry, inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.