Description

1-(2,3-Epoxypropyl)-4-Phenylpiperazine is a versatile epoxide-functionalized piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, combining the nucleophilic character of the piperazine nitrogen with the electrophilic epoxide ring, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological receptors or requiring piperazine-based pharmacophores.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, or plant growth regulators with enhanced activity.
• Polymer & Resin Modification: Used as a cross-linking agent or curing agent in epoxy resin systems to modify thermal and mechanical properties.
• Ligand & Catalyst Development: Serves as a scaffold for synthesizing novel chelating ligands or organocatalysts for asymmetric synthesis.
• Chemical Research & Development: Fundamental reagent in academic and industrial labs for exploring new organic reactions and constructing heterocyclic compounds.
• Material Science: Intermediate for creating advanced functional materials, such as dendrimers or surface-modifying agents.

Basic Information

Product Name	1-(2,3-Epoxypropyl)-4-Phenylpiperazine
CAS No.	72566-27-9
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	4-Phenyl-1-(oxiran-2-ylmethyl)piperazine; 1-Glycidyl-4-phenylpiperazine; N-(2,3-Epoxypropyl)-N'-phenylpiperazine; 1-(Oxiranylmethyl)-4-phenylpiperazine; 4-Phenyl-1-(2,3-epoxypropyl)piperazine; Phenylpiperazine glycidyl ether; EPHP
EINECS	Contact for details

Quality Control

Our 1-(2,3-Epoxypropyl)-4-Phenylpiperazine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.