Description

3,4,4Aα,5,6,7,8,8A-Octahydro-3α-Hydroxy-5,5,8Aβ-Trimethyl-2-Naphthalenecarbaldehyde is a high-purity, functionalized decalin derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and key intermediate for the development of complex molecules. It is particularly valuable for research and production in the pharmaceutical and fine chemical industries, where its unique stereochemistry and aldehyde functionality enable the construction of intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in steroid and terpenoid-related drug discovery.
• Fine Chemical Synthesis: Used as a key starting material or intermediate in the multi-step synthesis of complex fragrances, flavors, and specialty agrochemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Material Science: Serves as a monomer or functionalizing agent in the research of specialty polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for organic chemistry research in academic and industrial laboratories focused on natural product synthesis and methodology development.

Basic Information

Product Name	3,4,4Aα,5,6,7,8,8A-Octahydro-3α-Hydroxy-5,5,8Aβ-Trimethyl-2-Naphthalenecarbaldehyde
CAS No.	72537-20-3
Molecular Formula	C₁₄H₂₂O₂
Molecular Weight	222.32 g/mol
Synonyms	3α-Hydroxy-5,5,8aβ-trimethyl-3,4,4aα,5,6,7,8,8a-octahydro-2-naphthalenecarboxaldehyde; (3α,4aα,8aβ)-Decahydro-3-hydroxy-5,5,8a-trimethyl-2-naphthalenecarboxaldehyde; 3α-Hydroxy-5,5,8aβ-trimethylperhydro-2-naphthalenecarbaldehyde; 2-Naphthalenecarboxaldehyde, 3,4,4a,5,6,7,8,8a-octahydro-3-hydroxy-5,5,8a-trimethyl-, (3α,4aα,8aβ)-; Trimethyloctahydronaphthalenecarbaldehyde derivative.
EINECS	Contact for details

Quality Control

Our 3,4,4Aα,5,6,7,8,8A-Octahydro-3α-Hydroxy-5,5,8Aβ-Trimethyl-2-Naphthalenecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.