Description

1-(4-Amino-3-Chloro-Phenyl)-Ethanone is a versatile aromatic ketone intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both an amino and a chloro substituent, makes it a critical building block for constructing complex molecules with specific functionalities. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl-amine or aryl-ketone pharmacophores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its chlorinated aromatic ring is a valuable structural component.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing azo dyes and other complex colorants, leveraging its reactive amino group.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated system.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination or Suzuki coupling for creating biaryl structures.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.

Basic Information

Item	Details
Product Name	1-(4-Amino-3-Chloro-Phenyl)-Ethanone
CAS No.	72531-23-8
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	3'-Chloro-4'-aminoacetophenone; 1-(4-Amino-3-chlorophenyl)ethanone; 4-Amino-3-chloroacetophenone; 3-Chloro-4-aminoacetophenone; 4'-Amino-3'-chloroacetophenone; 1-Acetyl-2-chloro-4-aminobenzene; 2-Chloro-4-acetylphenylamine
EINECS	Contact for details

Quality Control

Our production of 1-(4-Amino-3-Chloro-Phenyl)-Ethanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and IR/NMR for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We are committed to meeting the high standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.