Description

4-(Trifluoromethyl)Thiobenzamide is a high-value fluorinated aromatic building block characterized by a thiobenzamide core functionalized with a trifluoromethyl group. This compound is essential for synthesizing advanced molecules where the combination of sulfur and fluorine atoms imparts unique electronic and physicochemical properties. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to enhance biological activity and environmental stability.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and organic semiconductors, due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluorinated thioamide moiety.

Basic Information

Product Name	4-(Trifluoromethyl)Thiobenzamide
CAS No.	72505-21-6
Molecular Formula	C8H6F3NS
Molecular Weight	205.20 g/mol
Synonyms	p-(Trifluoromethyl)thiobenzamide; 4-(Trifluoromethyl)benzenecarbothioamide; α,α,α-Trifluoro-p-thiobenzamide; Thiobenzamide, 4-(trifluoromethyl)-; Benzenecarbothioamide, 4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4-(Trifluoromethyl)Thiobenzamide adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and synthesis applications. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.