Description

cis-3-Chlorodihydro-3-Methyl-5-Phenylfuran-2(3H)-One is a high-value chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and functionalized furanone core make it a critical precursor for the development of complex, biologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structural motifs contribute to biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance and flavor compounds requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	cis-3-Chlorodihydro-3-Methyl-5-Phenylfuran-2(3H)-One
CAS No.	72406-94-1
Molecular Formula	C11H11ClO2
Molecular Weight	210.66 g/mol
Synonyms	cis-3-Chloro-3-methyl-5-phenyl-2(3H)-furanone; (3R,5S)-3-Chloro-3-methyl-5-phenyl-dihydrofuran-2-one; 3-Chloro-3-methyl-5-phenyl-2(3H)-furanone; 3-Chloro-3-methyl-5-phenyltetrahydro-2-furanone; 5-Phenyl-3-chloro-3-methyl-2(3H)-furanone; 72406-94-1; cis-3-Chloro-3-methyl-5-phenyl-dihydrofuran-2-one
EINECS	Contact for details

Quality Control

Our cis-3-Chlorodihydro-3-Methyl-5-Phenylfuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and chiral purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (cis-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.