Description

3-Chloro-2-Fluoroiodobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of chlorine, fluorine, and iodine substituents on the aromatic ring makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings due to the reactive iodine moiety.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Chloro-2-Fluoroiodobenzene
CAS No.	72373-82-1
Molecular Formula	C6H3ClFI
Molecular Weight	256.44 g/mol
Synonyms	1-Chloro-2-fluoro-3-iodobenzene; 2-Fluoro-3-chloroiodobenzene; 3-Chloro-2-fluoro-1-iodobenzene; Benzene, 1-chloro-2-fluoro-3-iodo-; 3-Chloro-2-fluorophenyl iodide; (3-Chloro-2-fluorophenyl)iodide
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoroiodobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.