Description

n-p-Tolyl-Malonamic Acid Ethyl Ester is a specialized organic intermediate characterized by its malonamic acid ester structure. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), especially those requiring a substituted malonamide or malonic acid derivative framework.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, or plant growth regulators where the tolyl and ester functionalities are integral.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocycles, peptidomimetics, or other specialty chemicals through reactions like cyclizations or condensations.
• Material Science Research: Investigated as a monomer or additive in the development of specialized polymers, coatings, or liquid crystals due to its aromatic and amide/ester groups.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies, catalysis research, and exploring new synthetic pathways.

Basic Information

Product Name	n-p-Tolyl-Malonamic Acid Ethyl Ester
CAS No.	72324-44-8
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	Ethyl (4-methylphenyl)aminocarbonylacetate; Ethyl 2-[(4-methylphenyl)carbamoyl]acetate; Ethyl (p-tolylcarbamoyl)acetate; N-(4-Methylphenyl)malonamic Acid Ethyl Ester; p-Tolylmalonamic Acid Ethyl Ester; Malonamic acid, N-(4-methylphenyl)-, ethyl ester; Acetamide, 2-ethoxy-2-oxo-N-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our n-p-Tolyl-Malonamic Acid Ethyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.