Description

5-Chloro-2-Cyclopropyliodobenzene is a high-value halogenated aromatic building block, specifically an iodobenzene derivative, with the CAS number 72233-02-4. This compound is essential for facilitating advanced cross-coupling reactions, enabling the efficient synthesis of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki, Negishi, and other palladium-catalyzed cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the cyclopropyl and iodine moieties for bioactivity.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-Chloro-2-Cyclopropyliodobenzene
CAS No.	72233-02-4
Molecular Formula	C9H8ClI
Molecular Weight	278.52 g/mol
Synonyms	2-Cyclopropyl-5-chloroiodobenzene; 1-Chloro-4-cyclopropyl-2-iodobenzene; 5-Chloro-2-cyclopropyl-1-iodobenzene; Benzene, 1-chloro-4-cyclopropyl-2-iodo-; (5-Chloro-2-cyclopropylphenyl)iodide
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Cyclopropyliodobenzene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and other spectroscopic methods. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.