Description

n-Boc-L-Phenylalaninal is a protected amino aldehyde derivative of L-phenylalanine, serving as a crucial chiral building block in organic synthesis. This compound matters for its role in facilitating the controlled synthesis of complex peptides and peptidomimetics, where the Boc (tert-butoxycarbonyl) group provides orthogonal protection. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs), peptide-based drugs, and advanced research compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and complex active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the phenylalanine aldehyde moiety with Boc protection.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries, ligands, and catalysts in stereoselective transformations.
• Bioconjugation & Labeling: Utilized in the preparation of modified peptides and proteins for biochemical research and diagnostic applications.
• Medicinal Chemistry Research: Employed in the design and library synthesis of novel drug candidates targeting various disease pathways.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in university and corporate laboratories.

Basic Information

Product Name	n-Boc-L-Phenylalaninal
CAS No.	72155-45-4
Molecular Formula	C₁₄H₁₉NO₃
Molecular Weight	249.31 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanal; Boc-Phe-H; Boc-L-Phenylalaninal; N-(tert-Butoxycarbonyl)-L-phenylalaninal; (S)-3-Phenyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanal; L-Phenylalaninal, N-Boc-; tert-Butyl (S)-(1-formyl-2-phenylethyl)carbamate; N-Boc-L-3-Phenylalaninal
EINECS	Contact for details

Quality Control

Our n-Boc-L-Phenylalaninal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.