Description

1-Ethyl-1H-Imidazole-5-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, where its imidazole core provides essential biological and chemical activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel fungicides, herbicides, and plant growth regulators that leverage the imidazole moiety for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized N-heterocyclic carbene (NHC) ligands and metal-organic catalysts used in asymmetric synthesis and polymerization.
• Material Science Research: Employed in the development of ionic liquids, conductive polymers, and corrosion inhibitors due to its ionic and coordination properties.
• Biochemical Research: Utilized as a scaffold in medicinal chemistry for designing enzyme inhibitors and receptor modulators.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity heterocyclic compounds.

Basic Information

Product Name	1-Ethyl-1H-Imidazole-5-Carboxylic Acid
CAS No.	71925-11-6
Molecular Formula	C6H8N2O2
Molecular Weight	140.14 g/mol
Synonyms	5-Carboxy-1-ethylimidazole; 1-Ethyl-5-imidazolecarboxylic Acid; 1-Ethyl-1H-imidazole-5-carboxylic acid; 1-Ethylimidazole-5-carboxylic Acid; 5-Carboxy-1-ethyl-1H-imidazole; 1-Ethyl-5-carboxyimidazole; 1H-Imidazole-5-carboxylic acid, 1-ethyl-; 71925-11-6
EINECS	Contact for details

Quality Control

Our 1-Ethyl-1H-Imidazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.