Description

3,4-Bis(Difluoromethoxy)Aniline is a specialized fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its core value lies in the unique reactivity of the aniline group combined with the electron-withdrawing and lipophilicity-enhancing properties of the difluoromethoxy substituents. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its fluorinated structure is critical for modulating biological activity, metabolic stability, and membrane permeability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where fluorine incorporation enhances efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in high-performance liquid crystal displays (LCDs).
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Utilized in the research and development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Complex Ligand Synthesis: Acts as a starting material for creating sophisticated ligands used in catalysis and material science.

Basic Information

Item	Details
Product Name	3,4-Bis(Difluoromethoxy)Aniline
CAS No.	71791-36-1
Molecular Formula	C9H8F4NO2
Molecular Weight	238.16 g/mol
Synonyms	3,4-Bis(difluoromethoxy)benzenamine; 1-Amino-3,4-bis(difluoromethoxy)benzene; 3,4-Bis(difluoromethoxy)phenylamine; Aniline, 3,4-bis(difluoromethoxy)-; 71791-36-1; 3,4-Difluoromethoxyaniline (ambiguous); Bis(difluoromethoxy)aniline
EINECS	Contact for details

Quality Control

Every batch of 3,4-Bis(Difluoromethoxy)Aniline is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Due to its sensitivity to light and oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.