Description

1,3-Dichloro-5-Iodo-2-Methoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams developing active ingredients, specialty chemicals, and functional materials that require precise halogenation for activity or further functionalization.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and pesticides, where its halogen atoms are crucial for bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring halogenated aromatic cores for specific electronic or physical properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: A versatile reagent for methodological development in cross-coupling reactions, such as Suzuki and Sonogashira couplings, and other halogen-based transformations.

Basic Information

Product Name	1,3-Dichloro-5-Iodo-2-Methoxybenzene
CAS No.	71742-42-2
Molecular Formula	C7H5Cl2IO
Molecular Weight	302.93 g/mol
Synonyms	2-Methoxy-1,3-dichloro-5-iodobenzene; 3,5-Dichloro-2-iodoanisole; 5-Iodo-1,3-dichloro-2-methoxybenzene; 1,3-Dichloro-5-iodo-2-methoxybenzene; 2-Iodo-3,5-dichloroanisole; Benzene, 1,3-dichloro-5-iodo-2-methoxy-; Anisole, 3,5-dichloro-2-iodo-
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-5-Iodo-2-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residue on Ignition	<0.1%
Related Substances (HPLC)	Total impurities <2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.