Description

(E)-3-Bromoacrylaldehyde is a versatile and reactive α,β-unsaturated carbonyl compound featuring a bromine atom at the β-position. This unique structure makes it a valuable high-purity building block for synthesizing complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in fine chemical, pharmaceutical, and advanced material industries for constructing heterocycles and other functionalized intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing heterocyclic frameworks like pyrazoles and isoxazoles.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its reactivity for molecular diversification.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Building Block: Employed in Michael addition reactions, cycloadditions, and palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) to introduce functionalized acrylate motifs.
• Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing novel chiral ligands or metal-organic complexes.

Basic Information

Product Name	(E)-3-Bromoacrylaldehyde
CAS No.	71653-11-7
Molecular Formula	C3H3BrO
Molecular Weight	134.96 g/mol
Synonyms	trans-3-Bromoacrolein; (E)-3-Bromo-2-propenal; 3-Bromoacrylaldehyde; 2-Propenal, 3-bromo-, (E)-; β-Bromoacrolein; Bromoacrolein
EINECS	Contact for details

Quality Control

Our (E)-3-Bromoacrylaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical applications, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive and reactive nature, it is recommended to store under an inert atmosphere for long-term preservation and to minimize decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity ((E)-isomer by GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.