Description

(4Ar)-4Aα,5,6,7,8,8A-Hexahydro-5α,6α-Dihydroxy-3-(1-Hydroxy-1-Methylethyl)-5,8Aβ-Dimethylnaphthalene-2(1H)-One is a complex, polycyclic organic compound with a highly functionalized decalin core structure. This compound is valued as a key chiral intermediate or building block in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive molecules. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical R&D departments for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of complex drug candidates, particularly those with steroid-like or terpenoid frameworks.
• Organic Synthesis Building Block: Used in advanced multi-step syntheses to introduce specific stereochemistry and functional groups (dihydroxy, ketone) into target molecules.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Natural Product Synthesis: Acts as a model compound or intermediate in the total synthesis of complex natural products with decalin or hydronaphthalene substructures.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals requiring precise stereochemical control.

Basic Information

Item	Detail
Product Name	(4Ar)-4Aα,5,6,7,8,8A-Hexahydro-5α,6α-Dihydroxy-3-(1-Hydroxy-1-Methylethyl)-5,8Aβ-Dimethylnaphthalene-2(1H)-One
CAS No.	71539-78-1
Molecular Formula	C17H28O4
Molecular Weight	296.40 g/mol
Synonyms	5,8a-Dimethyl-3-(2-hydroxypropan-2-yl)-4a,5,6,7,8,8a-hexahydro-4a,6a-dihydroxynaphthalen-2(1H)-one; 4a,5,6,7,8,8a-Hexahydro-5,8a-dimethyl-4a,6a-dihydroxy-3-(1-hydroxy-1-methylethyl)naphthalen-2(1H)-one; (4aR,5S,6aS,8aR)-5,8a-Dimethyl-3-(2-hydroxypropan-2-yl)-4a,5,6,7,8,8a-hexahydro-4a,6a-dihydroxynaphthalen-2(1H)-one; Decalin-2-one derivative; Polyhydroxy decalone derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.