Description

7-Fluoro-2H-Chromen-2-One is a fluorinated derivative of coumarin, a privileged heterocyclic scaffold in medicinal and materials chemistry. This compound matters as a versatile and high-value chemical building block for synthesizing advanced pharmaceutical intermediates and functional organic materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in fluorinated bioactive molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced fluorinated pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for fluorinated electron-transport or emissive layer materials in display and lighting technologies.
• Fluorescent Probe & Dye Synthesis: The coumarin core is ideal for creating fluorophores; the fluorine substitution allows fine-tuning of photophysical properties for sensing and imaging applications.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic synthesis, especially in fluorination and cross-coupling reactions.
• Material Science: Investigated as a monomer or additive for creating polymers with specific optical or electronic characteristics.

Basic Information

Product Name	7-Fluoro-2H-Chromen-2-One
CAS No.	71428-25-6
Molecular Formula	C9H5FO2
Molecular Weight	164.13 g/mol
Synonyms	7-Fluorocoumarin; 7-Fluoro-2H-1-Benzopyran-2-One; 7-Fluoro-2H-Chromen-2-One; 7-Fluoro-2-Oxo-2H-Chromene; 7-Fluorochromen-2-one; 7-Fluoro-1,2-Benzopyrone; 7-Fluoro-2H-1-Benzopyran-2-one; 7-Fluoro-2H-Chromen-2-One (7-Fluorocoumarin)
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2H-Chromen-2-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.