Description

Benzoic Acid, 4-Amino-5-Cyano-2-Hydroxy-, Methyl Ester (9Ci) is a specialized heterocyclic building block with a CAS number of 71408-00-9. This compound matters as a key intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists for constructing fused pyrimidine and quinazoline derivatives, which are core structures in many active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of quinazolinone and pyrimido[4,5-d]pyrimidine scaffolds for potential drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Dye and Pigment Synthesis: Serves as a building block for creating specialized colorants and functional dyes.
• Material Science: Investigated for the preparation of organic semiconductors and ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for methodological studies and library synthesis in medicinal chemistry programs.

Basic Information

Product Name	Benzoic Acid, 4-Amino-5-Cyano-2-Hydroxy-, Methyl Ester (9Ci)
CAS No.	71408-00-9
Molecular Formula	C10H9N3O3
Molecular Weight	219.20 g/mol
Synonyms	4-Amino-5-cyano-2-hydroxybenzoic acid methyl ester; Methyl 4-amino-5-cyano-2-hydroxybenzoate; 2-Hydroxy-4-amino-5-cyanobenzoic acid methyl ester; 4-Amino-2-hydroxy-5-cyanobenzoic acid methyl ester; Methyl 4-amino-2-hydroxy-5-cyanobenzoate; 9CI compound 71408-00-9; Benzoic acid, 4-amino-5-cyano-2-hydroxy-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Amino-5-Cyano-2-Hydroxy-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.