Description

(3E,4S)-3-Hexadecylidene-4α-Hydroxy-5α-Methyldihydro-2(3H)-Furanone CAS NO 71358-20-8 is a high-purity, synthetic lactone derivative characterized by its specific stereochemistry and long alkyl chain. This compound is valued for its role as a versatile chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for compounds requiring specific stereochemical configurations.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structural motif can contribute to biological activity.
• Fine Chemical Production: Acts as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring lactone functionalities.
• Academic & Industrial Research: Employed as a standard or reagent in methodological studies involving asymmetric synthesis and natural product mimicry.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique properties.

Basic Information

Item	Details
Product Name	(3E,4S)-3-Hexadecylidene-4α-Hydroxy-5α-Methyldihydro-2(3H)-Furanone
CAS No.	71358-20-8
Molecular Formula	C21H38O3
Molecular Weight	338.53 g/mol
Synonyms	(3E,4S)-3-Hexadecylidene-4-hydroxy-5-methyl-2(3H)-furanone; 4-Hydroxy-5-methyl-3-(1-pentadecenyl)-2(5H)-furanone; (E)-(4S,5S)-4-Hydroxy-5-methyl-3-(1-pentadecenyl)-2(5H)-furanone; 3-Hexadecylidene-4-hydroxy-5-methyl-2(3H)-furanone; Lactone derivative CAS 71358-20-8; (3E,4S)-Lactone intermediate; Chiral C21 lactone
EINECS	Contact for details

Quality Control

Our (3E,4S)-3-Hexadecylidene-4α-Hydroxy-5α-Methyldihydro-2(3H)-Furanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with stringent specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.