Description

5,6-Difluoro-2-Oxoindole is a high-purity fluorinated oxindole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecules with enhanced biological and physical properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where fluorine atoms can improve metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and organic electronic materials requiring specific fluorinated motifs.
• Chemical Biology Probe Development: Employed in creating fluorescent tags or molecular probes for studying biological pathways and enzyme activity.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new fluorination reactions.

Basic Information

Product Name	5,6-Difluoro-2-Oxoindole
CAS No.	71294-07-0
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	5,6-Difluoro-1,3-dihydro-2H-indol-2-one; 5,6-Difluorooxindole; 2-Oxo-5,6-difluoroindoline; 5,6-Difluoro-2-indolinone; 71294-07-0; 5,6-Difluoro-1H-indole-2,3-dione (tautomer); 5,6-Difluoro-2-oxo-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 5,6-Difluoro-2-Oxoindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.