Description

3,5,3',5'-Tetrafluorodiethylstilbestrol is a fluorinated synthetic estrogen analog, representing a high-value intermediate in advanced pharmaceutical research and development. Its strategic importance lies in its role as a key building block for creating novel, targeted therapeutic agents and sophisticated biochemical probes. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require precise, high-purity intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel fluorinated estrogen receptor modulators and other targeted therapeutic molecules.
• Biochemical Research: Used as a high-affinity ligand and probe in receptor binding studies to investigate estrogen receptor (ER) structure, function, and signaling pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new chemical entities with enhanced potency, selectivity, or metabolic stability.
• Reference Standard: Utilized as an analytical standard in method development and quality control for the quantification of related compounds in complex matrices.
• Academic Research: Applied in university and institutional labs for fundamental studies in endocrinology, oncology, and chemical biology.
• Development of Diagnostic Tools: Acts as a component in the development of assays and diagnostic kits for hormonal research.

Basic Information

Product Name	3,5,3',5'-Tetrafluorodiethylstilbestrol
CAS No.	71292-84-7
Molecular Formula	C18H16F4O2
Molecular Weight	340.32 g/mol
Synonyms	TF-DES; Tetrafluoro-DES; 4,4'-(1,2-Diethyl-1,2-ethenediyl)bis(2,6-difluorophenol); 3,5,3',5'-Tetrafluoro-4,4'-dihydroxystilbene; Diethylstilbestrol Tetrafluoride; DES-TF; 2,2'-(1,2-Diethyl-1,2-ethenediyl)bis(4,6-difluorophenol)
EINECS	Contact for details

Quality Control

Our 3,5,3',5'-Tetrafluorodiethylstilbestrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.