Description

3',5'-Difluoro-4'-Methoxypropiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, where its specific substitution pattern enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluoromethoxy or related pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the stability and bioactivity imparted by the fluorine atoms.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination reactions and constructing complex aromatic systems in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of tailored compounds and proprietary intermediates.

Basic Information

Product Name	3',5'-Difluoro-4'-Methoxypropiophenone
CAS No.	71292-82-5
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	1-(3,5-Difluoro-4-methoxyphenyl)propan-1-one; 3,5-Difluoro-4-methoxypropiophenone; Propiophenone, 3',5'-difluoro-4'-methoxy-; 4-Methoxy-3,5-difluoropropiophenone; 3,5-Difluoro-4-methoxy-1-propiophenone
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoro-4'-Methoxypropiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.