Description

[[n-(Trifluoromethyl)Amino]Carbonyl] Cyanide is a specialized organic building block featuring a reactive cyanide group adjacent to a trifluoromethyl-substituted urea moiety. This compound is valued for its unique reactivity profile, enabling the efficient introduction of both cyano and trifluoromethylamino carbonyl functionalities into target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing heterocyclic cores and complex molecules in drug discovery programs, particularly for candidates targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functional polymers and advanced organic materials with tailored electronic or surface properties.
• Fluorine Chemistry: An essential reagent for studying and applying new methodologies in fluorination and the synthesis of fluorinated compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological mechanisms and diagnostics.

Basic Information

Product Name	[[n-(Trifluoromethyl)Amino]Carbonyl] Cyanide
CAS No.	70856-23-4
Molecular Formula	C3HF3N2O
Molecular Weight	138.05 g/mol
Synonyms	N-Cyano-N'-(trifluoromethyl)urea; (Trifluoromethyl)carbamoyl cyanide; 1-Cyano-3-(trifluoromethyl)urea; Urea, N-cyano-N'-(trifluoromethyl)-; (Trifluoromethylamino)carbonyl cyanide; TFAC Cyanide
EINECS	Contact for details

Quality Control

Every batch of [[n-(Trifluoromethyl)Amino]Carbonyl] Cyanide is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.