Description

(4R,9α)-6α,10,16-Trihydroxy-9-Methyl-20-Norkaurane-18-Oic Acid 18,10-Lactone is a high-purity, complex diterpenoid lactone compound of significant interest in advanced pharmaceutical research and development. Its intricate kaurane-derived structure makes it a valuable intermediate or reference standard for the synthesis and study of bioactive molecules. This compound is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex natural product derivatives and potential drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in research and regulatory submissions.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of diterpenoid compounds.
• Natural Product Chemistry: Acts as a standard or starting material for the semi-synthesis of related kaurane-type natural products.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	(4R,9α)-6α,10,16-Trihydroxy-9-Methyl-20-Norkaurane-18-Oic Acid 18,10-Lactone
CAS No.	70775-66-5
Molecular Formula	C₂₀H₂₈O₅
Molecular Weight	348.43 g/mol
Synonyms	6α,10,16-Trihydroxy-9-methyl-20-norkauran-18-oic acid 18,10-lactone; (4R,9α)-6α,10,16-Trihydroxy-9-methyl-20-norkauran-18-oic acid γ-lactone; 20-Norkaurane-18-oic acid, 6α,10,16-trihydroxy-9-methyl-, 18,10-lactone, (4R,9α)-; Kaurane diterpenoid lactone derivative.
EINECS	Contact for details

Quality Control

Our (4R,9α)-6α,10,16-Trihydroxy-9-Methyl-20-Norkaurane-18-Oic Acid 18,10-Lactone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All batches undergo comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.