Description

(4R,9α)-7α,10,16-Trihydroxy-9-Methyl-20-Norkauran-18-Oic Acid γ-Lactone is a high-purity, structurally complex diterpenoid lactone of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a potential intermediate for the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of natural product derivatives, drug discovery, and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in oncology and metabolic disease pathways.
• Natural Product Synthesis: Used as a sophisticated starting material or intermediate in the total synthesis of complex diterpenoid natural products and their analogs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities and optimize biological activity.
• Process Chemistry Development: Serves as a reference standard or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or cellular receptors.
• Academic Research: Utilized in university and institutional laboratories for advanced organic chemistry projects and methodology development.

Basic Information

Product Name	(4R,9α)-7α,10,16-Trihydroxy-9-Methyl-20-Norkauran-18-Oic Acid γ-Lactone
CAS No.	70775-63-2
Molecular Formula	C19H28O5
Molecular Weight	336.42 g/mol
Synonyms	7α,10,16-Trihydroxy-9-methyl-20-norkauran-18-oic acid γ-lactone; 7α,10,16-Trihydroxy-9-methyl-20-norkauran-18-oate γ-lactone; 20-Norkaurane diterpenoid lactone; (4R,9α)-Kaurane derivative; 7α,10,16-Trihydroxy-9-methyl-20-norkauran-18-oic acid, 18,16-lactone; NSC 339586; A complex diterpenoid γ-lactone
EINECS	Contact for details

Quality Control

Our (4R,9α)-7α,10,16-Trihydroxy-9-Methyl-20-Norkauran-18-Oic Acid γ-Lactone is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.