Description

Nargenicin A1 CAS NO 70695-02-2 is a specialized macrolide antibiotic compound of significant interest in pharmaceutical research and development. Its primary value lies in its unique antibacterial activity, particularly against Gram-positive bacteria, making it a crucial intermediate for synthesizing novel therapeutic agents. This product is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers focused on developing new antibiotics and studying bacterial resistance mechanisms.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel antibiotic drugs and prodrugs.
• Antimicrobial Research: Used as a reference standard or active compound in microbiological studies to investigate mechanisms of action and resistance.
• Biochemical Tool: Employed in laboratory settings to study protein synthesis inhibition in bacteria.
• Veterinary Medicine Development: Potential application in the R&D of antibacterial treatments for animal health.
• Standards and Controls: Serves as a high-purity analytical standard for quality control and method validation in regulatory and research laboratories.

Basic Information

Product Name	Nargenicin A1
CAS No.	70695-02-2
Molecular Formula	C34H58O10
Molecular Weight	626.82 g/mol
Synonyms	Nargenicin; Antibiotic A 28086A; Lonomycin A; A-28086A; Antibiotic A28086A; Nargenicin A1; 70695-02-2; (2R,3S,4S,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10,14-tetrahydroxy-5,13-dimethoxy-3,4,8,12-tetramethyl-15-oxo-1-oxacyclopentadec-6-en-2-yl acetate
EINECS	Contact for details

Quality Control

Our Nargenicin A1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.