Description

Butanenitrile, 3-Bromo-2-Oxo- is a specialized brominated nitrile building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive nitrile group and a bromine-substituted carbonyl, makes it a versatile precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functional complexity into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic frameworks like pyrroles and pyridines.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Fine Chemical Building Block: Employed in the preparation of complex molecules for material science, dyes, and specialty polymers.
• Academic & Industrial Research: Serves as a valuable reagent in methodological development and exploratory chemistry for creating new carbon-carbon and carbon-heteroatom bonds.
• Ligand and Catalyst Development: The nitrile and carbonyl functionalities can be utilized to synthesize novel chelating agents and organocatalysts.

Basic Information

Product Name	Butanenitrile, 3-Bromo-2-Oxo-
CAS No.	70688-37-8
Molecular Formula	C₄H₄BrNO
Molecular Weight	162.98 g/mol
Synonyms	3-Bromo-2-oxobutanenitrile; 2-Oxo-3-bromobutyronitrile; 3-Bromoacetoacetonitrile; 3-Bromo-2-oxobutyronitrile; Bromoacetoacetonitrile; α-Bromoacetoacetonitrile; 3-Bromo-3-oxopropanenitrile (tautomeric form); Bromoacetylacetonitrile
EINECS	Contact for details

Quality Control

Our Butanenitrile, 3-Bromo-2-Oxo- is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged stability.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.