Description

[6E,10E,14E,(-)]-2,4,5,8,9,12,13,15A-Octahydro-3,6,10,14-Tetramethylcyclotetradeca[B]Furan is a complex, high-purity macrocyclic furan derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block or intermediate for the development of novel pharmaceuticals, agrochemicals, and specialty fragrances. It is primarily sought by R&D chemists and process development teams in fine chemical and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for anti-cancer or anti-infective agents.
• Agrochemical Research: Building block for developing novel pesticides or herbicides with specific stereochemical requirements for biological activity.
• Fragrance & Flavor Chemistry: Intermediate for creating unique macrocyclic musk or amber scent molecules in high-value perfumery.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers with tailored properties.
• Academic & Contract Research: Valuable reagent for methodological studies in total synthesis, catalysis, and stereochemistry.

Basic Information

Item	Details
Product Name	[6E,10E,14E,(-)]-2,4,5,8,9,12,13,15A-Octahydro-3,6,10,14-Tetramethylcyclotetradeca[B]Furan
CAS No.	70645-54-4
Molecular Formula	C18H30O
Molecular Weight	262.43 g/mol
Synonyms	(-)-Ambrox; (-)-Ambroxide; (6E,10E,14E)-2,4,5,8,9,12,13,15a-Octahydro-3,6,10,14-tetramethylcyclopenta[b][1]benzoxepin; (-)-Ambroxan; (-)-Ambrox DL; (3aS,5aR,9aS,9bR)-Dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan; (-)-Ambrofix; (-)-Amberketal
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to meet your R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.