Description

4-Isopropyl-1-tert-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane is a high-purity bicyclic orthoester compound, valued for its role as a versatile chemical intermediate and protecting group in advanced organic synthesis. Its unique cage-like structure provides exceptional stability under specific conditions, making it a critical reagent for constructing complex molecular architectures. This product is essential for research and development laboratories, pharmaceutical synthesis, and specialty chemical manufacturing where precise control over reaction pathways is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where acid-labile protecting groups are needed.
• Advanced Organic Synthesis: Serves as a key building block and protecting group for alcohols and diols in multi-step synthetic routes.
• Polymer Chemistry: Employed as a cross-linking agent or monomer precursor for specialty polymers with tailored properties.
• Material Science Research: Utilized in the development of novel organic frameworks and functional materials.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain high-value crop protection agents.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical transformations in laboratory settings.

Basic Information

Product Name	4-Isopropyl-1-tert-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane
CAS No.	70636-92-9
Molecular Formula	C11H20O3
Molecular Weight	200.27 g/mol
Synonyms	1-tert-Butyl-4-isopropyl-2,6,7-trioxabicyclo[2.2.2]octane; 4-Isopropyl-1-tert-butyl-2,6,7-trioxabicyclo[2.2.2]octane; Bicyclic orthoester; TBITBO; 1-(1,1-Dimethylethyl)-4-(1-methylethyl)-2,6,7-trioxabicyclo[2.2.2]octane; tert-Butyl isopropyl bicyclic orthoformate; Orthoester protecting group
EINECS	Contact for details

Quality Control

Our 4-Isopropyl-1-tert-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.