Description

4-[(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl]Morpholine is a versatile organoboron building block, specifically a morpholine-substituted boronic ester, that is critical for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex carbon-carbon bond formation.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate morpholine and boron-based functional groups.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Polymer & Material Science: Incorporated into the synthesis of functional polymers, organic electronic materials, and boron-containing advanced materials.
• Chemical Biology Probes: Utilized in the development of molecular probes and bio-conjugation reagents for studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory synthesis in both academic laboratories and industrial R&D centers.

Basic Information

Product Name	4-[(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl]Morpholine
CAS No.	70558-05-3
Molecular Formula	C11H22BNO3
Molecular Weight	227.11 g/mol
Synonyms	2-(Morpholin-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ylmethyl)morpholine; Morpholine, 4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-; (Morpholinomethyl)boronic acid pinacol ester; 4-(Pinacolborylmethyl)morpholine; N-[(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]morpholine
EINECS	Contact for details

Quality Control

Our 4-[(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.