Description

Iodomethylboronic Acid, Pinacol Ester is a versatile and valuable organoboron building block, specifically a protected boronic acid derivative. This compound is essential for facilitating efficient cross-coupling reactions, such as Suzuki-Miyaura couplings, due to the enhanced stability provided by the pinacol ester group. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require the introduction of functionalized methylene groups.
• Material Science: Serves as a building block for creating organic electronic materials, liquid crystals, and polymers with tailored properties.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, bioconjugation reagents, and activity-based protein profiling (ABPP) agents.
• Organic Synthesis Research: A fundamental tool in academic and industrial R&D labs for constructing complex carbon skeletons and exploring new synthetic methodologies.
• Ligand & Catalyst Development: Used to synthesize novel bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	Iodomethylboronic Acid, Pinacol Ester
CAS No.	70557-99-2
Molecular Formula	C7H14BIO2
Molecular Weight	267.90 g/mol
Synonyms	Pinacol (Iodomethyl)boronate; (Iodomethyl)boronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-(iodomethyl)-1,3,2-dioxaborolane; 2-(Iodomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Iodomethylboronic Acid Pinacol Ester; Iodomethyl-Bpin; BpinCH2I
EINECS	Contact for details

Quality Control

Our Iodomethylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.