Description

2H-1,2-Oxazine-3-Carboxamide, 2-(Chloroacetyl)-5,6-Dihydro-n-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both oxazine and carboxamide functionalities activated by a chloroacetyl group, making it a versatile precursor for constructing complex nitrogen-oxygen heterocycles. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting neurological or anti-infective pathways.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, leveraging its reactive chloroacetyl group for further derivatization.
• Chemical Research: Acts as a fundamental building block in methodological studies and the synthesis of complex heterocyclic libraries for high-throughput screening.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, or functional materials requiring specific nitrogen-oxygen containing frameworks.
• Ligand and Catalyst Development: Potential use in the design of novel chelating ligands or organocatalysts due to its amide and heterocyclic structure.

Basic Information

Product Name	2H-1,2-Oxazine-3-Carboxamide, 2-(Chloroacetyl)-5,6-Dihydro-n-Methyl- (9Ci)
CAS No.	70236-00-9
Molecular Formula	C8H11ClN2O3
Molecular Weight	218.64 g/mol
Synonyms	2-(Chloroacetyl)-N-methyl-5,6-dihydro-2H-1,2-oxazine-3-carboxamide; N-Methyl-2-(chloroacetyl)-5,6-dihydro-2H-1,2-oxazine-3-carboxamide; 2H-1,2-Oxazine-3-carboxamide, 2-(chloroacetyl)-5,6-dihydro-N-methyl-; 70236-00-9; 2-(Chloroacetyl)-N-methyl-4,5-dihydro-2H-1,2-oxazine-3-carboxamide; Methyl 2-(chloroacetyl)-5,6-dihydro-2H-1,2-oxazine-3-carboxylate derivative
EINECS	Contact for details

Quality Control

Our 2H-1,2-Oxazine-3-Carboxamide, 2-(Chloroacetyl)-5,6-Dihydro-n-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key specifications are available upon request, providing full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.