Description

2,3-o-Isopropylidene-L-Apiose is a protected derivative of the rare branched-chain pentose sugar, L-apiose. This compound is a crucial chiral building block and intermediate in synthetic organic chemistry, particularly for the preparation of complex carbohydrates and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and advanced glycosylation studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
• Glycochemistry Research: Used as a protected sugar moiety for the construction of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Biochemical Probe Development: Acts as a precursor for labeled apiose derivatives used in metabolic pathway studies and enzyme substrate analysis.
• Natural Product Synthesis: A critical starting material for the total or semi-synthesis of natural products containing the unique apiose sugar unit.
• Process Chemistry: Employed in scale-up routes for the production of specialized fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	2,3-o-Isopropylidene-L-Apiose
CAS No.	70147-51-2
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	L-Apiose 2,3-Acetonide; (2R,3S,4R)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; 2,3-O-Isopropylidene-β-L-apiose; 2,3-O-Isopropylidene-L-apiofuranose; 1,2-O-Isopropylidene-L-apiose; L-Apiose acetonide; Apiose 2,3-acetonide
EINECS	Contact for details

Quality Control

Every batch of 2,3-o-Isopropylidene-L-Apiose is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, optical rotation, and spectroscopic confirmation (NMR, IR). A Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades or analytical packages are available to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.